Enduring Hearts is a nonprofit charity that awards operating grants to established members of academic staff at universities, transplant centers and research institutes for research projects in organ transplantation.
Hospital for Sick Children, University of Toronto
Enduring Hearts is funding $35,000 to complete a $50,000 research grant, directed towards ‘Immunogenetic Markers of Extreme Clinical Phenotypes of Post-Transplant Lymphoproliferative Disorder: A Pilot Project.’
The study addresses immune-related markers that could serve as novel targets for assays, aimed at identifying patients who are at greatest risk of poor outcomes from Epstein Barr virus-related post-transplant lymphoproliferative disorder.
Emory University School of Medicine
Enduring Hearts is fully funding a $25,000 research grant for a collaborative research effort between Duke University and Emory University, towards ‘Prevention of Homograft Induced Cardiac Allograft Vasculopathy in Pediatric Heart Transplantation.’
This study is evaluating the post heart transplant humoral response, with MHC matching/mismatching homograft and possible interventions.
2015 ISHLT Presentation by Shriprasad Deshpande, MD, MS
Dr. Shriprasad Deshpande attended the 2015 International Society for Heart & Lung Transplantation (ISHLT) Conference in Nice, France, to deliver a presentation on the accepted abstract from his research, ‘Old Problems — New Solutions?: Is Chimerism in Cardiac Transplant Allografts an Indicator of Decreased Longevity? Utilizing Quantitative Real-Time PCR in Pediatric Patients.’
The research looked at the chimerism of cardiac myocytes in a transplanted heart, with a focus on assessing the participation of host (recipient) in the cardiac regenerative process of the transplanted heart, by qualifying the degree of chimerism.
Dr. Shriprasad Deshpande is a pediatric cardiologist with the Sibley Heart Center Cardiology, and an assistant professor of pediatrics at Emory University School of Medicine.
Dr. Deshpande obtained his medical degree from Lokmanya Tilak Medical College, in Mumbai, India, in 1998. He completed his residency in pediatrics at the University of Iowa Hospitals and Clinics in 2007. From 2007 to 2010, Dr. Deshpande was a fellow in pediatric cardiology, and an advanced fellow in pediatric cardiac intensive care from 2010 to 2011, at Children’s Healthcare of Atlanta.
Monroe Carell Jr. Children’s Hospital at Vanderbilt
Enduring Hearts is fully funding $68,029.92 research project at Vanderbilt University which is studying “2D speckle tracking echocardiography for non‐invasive surveillance of rejection and coronary disease in pediatric heart transplant recipients”.
This research aims to assess the ability of 2D speckle tracking to provide earlier identification of both rejection and coronary disease in pediatric heart transplant patients.
Vanderbilt University, Justin Godown, M.D.
Dr. Justin Godown is an Assistant Professor of Pediatrics at Vanderbilt University. He graduated from the University of Rochester School of Medicine and Dentistry in Rochester, N.Y. in 2008, and received his pediatric residency at the University of North Carolina Hospital in Chapel Hill.
He is part of the faculty at the Thomas P. Graham Jr. Division of Cardiology at Vanderbilt. The Thomas P. Graham Division is a national leader in pediatric cardiac research and treatment. Enduring Hearts is proud to fund one of their current projects, which studies “2D speckle tracking echocardiography for non‐invasive surveillance of rejection and coronary disease in pediatric heart transplant recipients”.
Dr. Godown recently updated Enduring Hearts on the project:
“We have identified 822 echocardiograms from heart transplant recipients and normal controls which will be included in our analysis. To date, we have completed strain measurements on 546 echocardiograms (66% complete). Therefore, we are well on our way to completing data collection and I anticipate that data collection should be on track for completion this summer as anticipated. This project would not be possible without your support and we truly appreciate your help in facilitating this important work.”